Epidermal development Factor Receptor Mutation in Lung Adenocarcinomas Relationship with CT Characteristics and Histologic Subtypes

Epidermal development Factor Receptor Mutation in Lung Adenocarcinomas Relationship with CT Characteristics and Histologic Subtypes
  • From the Departments of Radiology (H.J.L.) and Pathology (Y.K.J., D.H.C.), Seoul nationwide University Hospital, 28 Yeongeon-dong, Chongno-gu, Seoul 110-744, Republic of Korea; Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Cancer analysis Institute, Xenotransplantation analysis Center, Clinical analysis Center, Seoul National University College of Medicine, Seoul, Republic of Korea (Y.T.K., C.H.K.); Department of Clinical Radiology, University Hospital MГјnster, MГјnster, Germany (T.P.); and Department of Radiology, Columbia University Medical Center, New York, NY (B.Z., Y.T., L.H.S., T.P.).
  • Address communication to H.J.L. (e-mail [email protected] ).

Abstract

Function

To retrospectively recognize quantitative computed tomographic (CT) features that correlate with epidermal growth factor receptor (EGFR) mutation in surgically resected lung adenocarcinomas stratified by the Global Association for the research of Lung Cancer (IASLC), United states Thoracic Society (ATS), and European breathing Society (ERS) category in an eastern Asian cohort of patients known to have high prevalence of EGFR mutations. ...